Winnipeg Free Press

Winnipeg Free Press (Newspaper) - April 29, 1990, Winnipeg, Manitoba The Anatomy of a High addiction researchers Are beginning to understand How addictive drugs cause their special effects on the for including the effect is to intensify the transmission of signals among brain d drug user inhales cocaine molecules in i like enters bloodstream i through blood carries it throughout the within seconds it reaches the fast Ocuto set in the Brash pet Surti the limbic system in the Middle of the the effect occurs at the Points where fibres from one nerve cell almost touch the surface of h b cocaine molecules Block route by which dopamine would reenter Fps transmitter they bind to of tit dopamine a4 i More and More dopamine accumulates in the synaptic space and keeps stimulating the receiving the cocaine user feels this As a d a c relays a signal by releasing messenger caned into the synaptic dopamine drifts across the space and fits into receptors on the surface of the receiving this triggers an electrical signal that is relayed through the then the dopamine molecules break away from the receptors and go Back into the transmitter to be cocaine euphoria probed by William Booth the Washington Post Baltimore no one knows exactly what a Squirrel Monkey feels when it does but government scientists at the addiction research Centre Here know this a Monkey will flip a switch for hours just to get another dose of and just As some humans will go on a Binge of so too will a Monkey hit the switch for More and More cocaine until researchers Stop the but scientists caution that just because they can get a Monkey to feed its addiction so it does not necessarily support the popular belief that cocaine is the most addictive of abused they the reason the animal keeps hitting the lever May just be because cocaine makes the Monkey Supe Alert and pathway a Monkey might be just As addicted to but after a few in contrast to cocaine the Monkey might Stop hitting the lever because it feels sleepy or in the last few drug researchers have Learned an enormous amount about not Only do they know More about its True addictive they now at last have a rough idea of How cocaine produces its addiction scientists have for that the drug stimulates a still mysterious pathway in the brain that is involved in feelings of pleasure and some they now know at least one Region of the brain where cocaine does its a Structure called the nucleus which is responsible for helping humans Orient and move toward things they find whether the object of their desire is a member of the opposite a Fine wine or a Rock of crack special receptor in researchers know the exact molecular site in the nucleus acc Bens where the cocaine molecule binds to its special this in turn has led to a better understanding of How cocaine acts to overstimulated certain nerve cells in the a phenomenon that makes users feel armed with this new drugs Are being developed to treat the worst symptoms of to suppress cocaine craving and to reduce cocaine associated when a user smokes crack in a researchers believe he is employing one of the most efficient drug delivery systems in both animals and scientists smoked cocaine reaches the brain so quickly that it is almost impossible to distinguish a dose delivered by intravenous injection from a dose delivered by a Glass How fast does it get to the brain were not its too fast to measure in the said Jonathan a behavioural pharmacologist at the addiction research a Branch of the National Institute on drug Katz said he assumes crack cocaine reaches the brain in unlike snorting cocaine a relatively slow and inefficient smoking crack delivers the drug directly to the where it is readily absorbed by the pumped once through the heart and then up to the a single significant dose of cocaine in other enough to get a person with a history of cocaine use High increases boosts blood pressure and May double heart fatigue and depression a subject feels Friendly and some scientists describe this collection of sensations As while a full explanation of How cocaine produces euphoria remains researchers do know that the drug appears to affect the limbic the part of the brain involved in the powerful emotional of which the bes known Are those important to human such As the primal urges to flee and while several components of the limbic system Are under the one area that appears to get the most action is the nucleus the nucleus acc Bens is uniquely situated to communicate Between the limbic system and the part of the brain called the motor which directs when you see a pretty girl and Alert to her presence and Orient toward or when you smell a Good Bordeaux wine sauce and move toward the it is the nucleus acc Bens that is helping you Orient and move toward those things you perceive As said George a psych pharmacologist at the research Institute of the Scripps clinic in san chemical messenger scientists believe that cocaine stimulates the nucleus acc Bens by meddling with a special chemical messenger called in the nucleus cocaine enters the tiny space where one nerve cell almost touches a sort of no mans land called the synaptic for one nerve cell to transmit a signal to it must make the signal Cross the synaptic to do this a Neuron releases a Load of dopamine each dopamine molecule travels across the briefly attaches itself to a receptor on the receiving cell and then Heads Back into the Neuron from which it was stops the dopamine from returning to the Neuron that released according to Michael Kuhar of the addiction research it forces the dopamine to remain in the synaptic where it keeps stimulating the receiving Neuron Over and Over in a it is not the cocaine that makes a user it is the dopamine that lingers in the synaptic Over stimulating the nucleus Lovesick Parrot generates in video laughs mount Lake a a Parrot with a passion for a porcelain Bird is getting the cold shoulder from his lady love and a lot of laughs from Maynard on sided Romance with the Bir shaped which he woos with an ardent court ship will get a North Ameri can television audience unrequited love for a Bir shaped birthdays bottle has made Maynard a Star on Abc tvs funniest Home videos 7 tonight on sky and Michelle Gladding and Mark who live with the Blue streaked red Lorius Parrot in this Seattle Are Richer because of his antics and have a shot at the shows grand i just believe that some thing Maynard does every Day is extremely funny to everyone said whose Larry captured Maynard head Bobbing mating dance on video and sent the footage to the television on april the couple got a Call from two Days they were treated to a firs class flight to los accommodations in Hollywood and a private dressing room at the television Stu dozens of Home video clips Are aired each week on the but Maynard was one of three chosen to compete for the weekly prize and he when they return to Hollywood in Midway to tape the grand prize Maynard will too travelling first class and staying in his own hotel holy Cross holding annual fair today hey Tom will hold annual fair today Between 11 and 5 at holy Cross 290 Bubuc utes a dhary of the fraternal met of aerie will hold a Tea and Bazaar today Between noon and at the eagles 3459 Pembina Little Britain Highway will hold a Spring Tea today Between and ladles of vital Parish in fort Garry will hold its annual Spring Tea today Between 1 and 4 at Parish 1639 Pembina Charles 331 Charles will hold a Spring Tea and open House today Between 1 and Over eaten Anonymous will hold an informational meeting today be tween 1 and 4 at the Centennial i 251 Donald pol Lorama Pavilion ambassador and youth ambassador inauguration will be held at 2 today at the University of Winnipeg athletic Anola roman Catholic Church will hold its annual Spring Tea today be tween 2 and 4 at the Anola Community ladles auxiliary to the Royal Ca Nadian legion the Duke of Branch will hold a Spring Tea today Between 2 and 4 at the Branch 171 Bannatyne Winnipeg spiritualist Church will hold a psychic Tea today Between 2 and at the promenade on the 367 Ellice admission readings Cameron association in Canada will hold the regiments 80th birth Day party today Between 3 and 10 in the Dieppe Henderson High Way 3600 Devries tickets couples Westminster United Maryland will hold two con certs by organist of the Salt Lake billboard for the column should be received a week to Advance of the Send them to Winnipeg free fourth 300 Cartton r3c they Are made free of City mormon Clay today at 3 and 8 tickets at the door jamaican honorary consulate meets today at 4 at 259 Watt ladles of the Church of the annunciation of will hold a Spring dinner today Between 4 and at the Woodlands Community West India Canadian anglican Fellowship will hold a Spring Community gathering today at at the holy Trinity anglican Donald Street and Graham hymns for an april a musical Celebration of the 65th anniversary of the United Church of will be held tonight at at Andrews River Heights United 255 Oak Winnipeg chamber music society will hold its final concert of the season tonight at 8 at the Muriel Richardson Winnipeg Art tickets students women Branch of the association of United ukrainian canadians will hold a rummage Sale tomorrow Between 9 and 1 at 591 Prit Chard Kildonan Transcona seniors will hold a seniors Public forum tomorrow be tween and noon at Bronx Park Community 131 Canadian mental health association will hold presentations on work ing together for mental to Morrow to Friday Between noon and 1 at the Centennial 251 Donald space tomatoes Ripe for exploitation its hard to two weeks have passed since the threat of the mutant killer space tomatoes made and there Hast been so much As a a miniseries or the appearance of a single Tomato activist on How Long does it take creative minds to get into for crying out loud the Story is a Jaclyn Smith and Jack Nicholson could be cast As two astronauts who return to Earth with the they warn the head of played by Ned of the suspect nature of the but Ned tells their or played by Joyce to go with them because seedlings sell space the starts Are sent out to Educa tors throughout the but one played by Sandy is she also uncovered the Asbestos there Are a lot of dark car breaking and foreign but you get the its a by the time Steven Spielberg comes out with his youll never touch another Tomato As Long As you the simple truth is that Art Hast imitated life for some it is there int a week goes by that you cant flip the to dial and real life stories of mystery and you begin to make it the old saw about a Guy who commits a crime when asked if he wants to Call his Call my never been More of a Erma Bombeck we not Only want our news interpreted for we also want it choreographed and sponsored to make it More it was re ported that even former president Ronald Reagan hated to read re so he requested those apply ing for something make a video he could serial surrogate mothers and spies quickly make the Transi Tion from Small print to to screen with a Little fiction thrown in to make it seem less the subject matter seems to follow a we went from losing Hearm films to baseball to War the vegetables time has i cannot imagine Why it is taking so the material is All it goes without saying that the teen age mutant ninja Tomato is going to be a i also have High Hopes for driving miss Bay the Story of a trucker who drives vegetables to the Market and talks to for two it take anyone Long to put together a script for George the the Sim ple Story of a Man whose Only escape from being served the dreaded vege table by his Mother was to get elected anyone want to do lunch Universal press Syndicate Inverness resort four Star Comfort nestled in a peaceful natural Selling Only Miles from Winnipeg offering 24 some private whirlpools 5 night escape 1180 to off boat and Mucor run us complimentary Mountain bikes 13695336 by Erbun Lake in the Whit Shell Sandy payment Fitzgerald lordy lordy Sandy is 40 party on dude to mom love Keith and families tvs Cene up Odate plus Quick reference prime time every Manitoba Spring Craft Sale Winnipeg convention cen1re May 1990 opening wednesday May 2 at 7 00 p m thurs Fri 11am 10 p m sat Sun 1 i a m 6 p m adults 54 seniors s3 just Luck saved Ben Franklin new York times news service Why want Ben Franklin killed with his Kite Experiment in the lightning storm he was said David a weather a fellow russian experimenter was killed doing the same Experiment in the same in Ludlum Franklin probably survived because he was not actually standing in a while the russian probably a wet string could have provided enough conductivity to Lead a potentially lethal electrical charge through his body to the by Franklin had been con ducting scientific experiments for about seven his work with electrical batteries made him curious to find out if lightning was Ludlum the exact Date when he flew his Kite with the key attached in the lightning storm is not recorded in Franklins autobiography re searchers suspect it was in local records for the weather in Philadelphia Are not Complete enough to determine when there might have been a storm with is regular soap a Good anti septic science but washing the hands with soap and water does remove bacteria and other Micro Orga because soap or detergent Breaks Down the surface tension so water can lift germs from the the Stream of water carries away Many but they Are not for real Antiseptic in other words the killing of a stronger such Asio Dine or Hydrogen must be applied to the according to the american medical Assoc a in Are not As Strong As which Are defined As bacteria killing substances that Are too Strong to apply to the achieving a truly or environment to protect a surgical patient from in for example is even More and involves disinfectants and sterilization such As subjecting surgical equipment to High pressure steam in an irradiation with ultraviolet Light or x rays also kills but Wash your hands Franklin Likely survived by not standing in ;