Winnipeg Free Press (Newspaper) - June 16, 2012, Winnipeg, Manitoba
C M Y K PAGE A18
A 18 WINNIPEG FREE PRESS, SATURDAY, JUNE 16, 2012 SCIENCE winnipegfreepress. com
L ONDON - For the first time,
doctors have successfully transplanted
a vein grown with a patient's
own stem cells, another example
of scientists producing human body
parts in the lab.
In this case, the patient was a 10- yearold
girl in Sweden who was suffering
from a severe vein blockage to her
liver. Last March, the girl's doctors decided
to make her a new blood vessel
to bypass the blocked vein instead of
using one of her own or considering a
liver transplant.
They took a nine- centimetre section
of vein from a deceased donor and
stripped it of all its cells, leaving just a
hollow tube. Using stem cells from the
girl's bone marrow, they grew millions
of cells to cover the vein, which took
about two weeks. The new blood vessel
was then transplanted into the patient.
Because the procedure used her own
cells, the girl did not have to take drugs
to stop her immune system from attacking
the new vein, as is usually the
case in transplants involving donor tissue.
" This is the future for tissue engineering,
where we can make tailor- made
organs," said Suchitra Sumitran- Holgersson
of the University of Gothenburg,
one of the study's authors.
She and colleagues published the
results of their work online Thursday
in the British medical journal Lancet .
The work was paid for by the Swedish
government.
The science is still preliminary and
one year after the vein was transplanted,
it needed to be replaced with
another lab- grown vein when doctors
noticed the blood flow had dropped. Experts
from University College London
raised questions in an accompanying
commentary about how cost- effective
the procedure might be, citing " acute
pressures" on health systems that
might make these treatments impractical
for many patients.
- The Associated Press
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Girl's stem
cells used
to grow
new vein
By Maria Cheng
LONDON - Diesel fumes cause cancer,
the World Health Organization's cancer
agency declared this week, a ruling it
said could make exhaust as important
a public health threat as second- hand
smoke.
The risk of getting cancer from
diesel fumes is small, but since so many
people breathe in the fumes in some
way, the science panel said raising the
status of diesel exhaust to carcinogen
from " probable carcinogen" was an important
shift.
" It's on the same order of magnitude
as passive smoking," said Kurt Straif,
director of the International Agency for
Research on Cancer department that
evaluates cancer risks. " This could be
another big push for countries to clean
up exhaust from diesel engines."
Since so many people are exposed
to exhaust, Straif said there could be
many cases of lung cancer connected
to the contaminant. He said the fumes
affected groups including pedestrians
on the street, ship passengers and
crew, railroad workers, truck drivers,
mechanics, miners and people operating
heavy machinery.
The new classification followed a
weeklong discussion in Lyon, France,
by an expert panel organized by the
IARC. The panel's decision stands as
the ruling for the IARC, the cancer
arm of the World Health Organization.
- The Associated Press
Diesel fumes
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as passive
smoking: WHO
A_ 18_ Jun- 16- 12_ FP_ 01. indd A18 6/ 15/ 12 5: 16: 49 PM
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