Winnipeg Free Press (Newspaper) - October 31, 2025, Winnipeg, Manitoba
FRIDAY, OCTOBER 31, 2025
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NEWS I CANADA / WORLD
COVID in pregnancy tied to autism, developmental issues, study says
CHILDREN born to mothers infected
with COVID-19 during pregnancy
faced a higher risk of autism, along
with other neurological differences
such as delays in speech and motor
development, according to a study pub-
lished Thursday.
The analysis of more than 18,100
births in Massachusetts, published in
the journal Obstetrics and Gynecology,
is among the largest studies to date
examining children born to women
who contracted the virus starting in the
early months of the pandemic through
some of 2021, before vaccines were
widely available.
The study’s authors emphasized that,
as an observational study, the findings
do not prove that COVID-19 causes the
conditions diagnosed in children, but
rather signal an association between
maternal infection and these outcomes.
And the risk of such a diagnosis, even
while elevated for women, remains
extremely low, said Andrea G. Edlow,
a physician scientist at Mass General
Hospital and an associate professor of
obstetrics and gynecology at Harvard
Medical School.
“It’s not that every pregnant woman
with COVID-19 in pregnancy needs to
think that her child is going to have
autism,” Edlow, a co-author, said.
“Overall, the absolute risk is not ex-
tremely high.”
Public health experts say the find-
ings underscore the importance of
COVID-19 vaccination during preg-
nancy, noting that protecting expect-
ant mothers helps safeguard both their
health and that of their babies. The re-
sults come at a time when coronavirus
vaccination rates have declined.
This spring, Health Secretary Robert
F. Kennedy Jr. — a longtime vaccine
skeptic — announced that the Centers
for Disease Control and Prevention
would no longer recommend the cor-
onavirus vaccine for healthy pregnant
women, prompting widespread criti-
cism from public health experts.
The American College of Obstetri-
cians and Gynecologists continues to
recommend vaccination and federal
officials now say all Americans re-
gardless of risk factors should consult
a medical provider about getting a cor-
onavirus vaccine.
The Trump administration has inten-
sified its scrutiny of coronavirus vac-
cine policies while promoting claims
that taking Tylenol during pregnancy
may increase the risk of autism.
There are currently no scientific
studies that show acetaminophen dur-
ing pregnancy causes autism, accord-
ing to many medical experts, who warn
that fevers mothers experience during
pregnancy can also be harmful.
Mary Ann Comunale, an associate
professor at Drexel University’s Col-
lege of Medicine, said the study offers
important evidence-based information
for discussion between a clinician and
their patient.
“This is particularly important in the
current climate of vaccine hesitancy,”
said Comunale, who was not involved in
the Massachusetts study.
In the new study, researchers exam-
ined medical records between March
1, 2020 and May 31, 2021. Among 861
women who had tested positive for the
coronavirus during pregnancy, 140
gave birth to a child who would receive
a neurodevelopment diagnosis by the
age of three.
Few had received vaccinations, re-
searchers said. Future studies of lar-
ger populations are needed to reveal
the potential risk for women who re-
ceived coronavirus vaccinations, said
Edlow and co-author Roy H. Perlis, a
Mass General researcher and Harvard
psychiatry professor.
The research builds on a growing
body of work about the impact of viral
infection during pregnancy and fetal
health. There’s strong evidence that
some viruses such as rubella, varicel-
la-zoster and Zika may directly cause
fetal injury.
In 2015 and 2016, the World Health
Organization declared a public health
emergency when the Zika virus was
spreading in Latin America and was
linked to hundreds of births of children
with microcephaly, a condition charac-
terized by an abnormally small head
and underdeveloped brain.
Scientists believe it is rare for res-
piratory viruses such as flu and SARS-
CoV-2, which causes COVID-19, to
cross the placental barrier and that the
impact on the fetus may be because of a
mother’s immune response.
One possible culprit may be inflam-
mation, which results in the release of
signalling molecules that may influ-
ence how neurons — the working unit
of the nervous system — in the brain
grow, connect and migrate.
Flu and COVID-19 have been linked
to obstetric complications such as pre-
term birth, but the evidence regard-
ing longer-term impacts on children’s
neurodevelopment has been more
mixed — with some studies showing
small increases in diagnoses and others
showing no effect.
Edlow explained that “if the fetus’
immune system gets really revved
up, that could have downstream con-
sequences, not just for the developing
brain, but also for the metabolic sys-
tem, the liver, the pancreas, the heart,
the adipose tissue.”
She said that in addition to neuro-
developmental diagnoses, other out-
comes could include obesity and meta-
bolic syndrome, or insulin resistance
later in life.
Researchers noted several weak-
nesses in the study. Lisa Croen, senior
research scientist at the Kaiser Perma-
nente Northern California Division of
Research, said that maternal condi-
tions such as obesity, hypertension, ges-
tational diabetes were not controlled
for in any of the analyses “so findings
could be confounded by these factors.”
She said more research is needed,
but the results do “provide addition-
al, strong rationale for supporting
COVID-19 vaccination in pregnancy.”
— The Washington Post
DAVID OVALLE,
ARIANA EUNJUNG CHA
A
RICHMOND, B.C., councillor says
a company based in the city has
been refused financing for what
she says is a $100 million project be-
cause of uncertainty over their site due
to the Cowichan Tribes Aboriginal title
ruling.
Coun. Alexa Loo said the company,
which she wouldn’t name, is now work-
ing with the provincial government to
get the certainty it needs to go ahead
with what she described as a manufac-
turing facility in the title area.
“This company, they had a deal al-
ready in place with one of the major
banks to finance their project,” Loo
said in an interview on Wednesday,
identifying the potential lender as Na-
tional Bank.
She said the company already owns
land for the planned facility in the Co-
wichan area, but was told by the bank
that it “doesn’t want to deal with new
projects at this time” because of the
uncertainty stemming from the court
ruling.
“So, it’s not an existing mortgage that
is being pulled … but they are cancel-
ling this project for now, because of
the uncertainty over the land title and
because the appeal process could take
anywhere from three to five years to 10
years,” Loo said.
Asked if it had denied funding to such
a project in the Cowichan title area be-
cause of the case, National Bank said
in a one-sentence response that “no
specific directive has been given to our
teams regarding this court ruling.”
Loo had previously spoken of the situ-
ation with residents before a meeting
with landowners on Tuesday about the
impact of the landmark case that con-
firmed the tribes’ Aboriginal title over
about 750 acres of private and govern-
ment-owned land in Richmond.
When asked about the case, The City
of Richmond provided a statement
from Loo saying the firm “is loathe to
discuss” its financial situation publicly.
In August, a B.C Supreme Court
judge ruled the Cowichan Tribes have
Aboriginal title over the land on the
Fraser River, that Crown and city titles
on the land are defective and invalid
and that the granting of private titles
on it by the government unjustifiably
infringed on the Cowichan title.
The province, Richmond and other
defendants have said they plan to ap-
peal the ruling that has triggered con-
cern about the implications for private
land ownership both in the Cowichan
area and beyond.
The provincial government said it’s
collecting information from property
owners, including whether they have
been able to get mortgages or financing
since the decision and Premier David
Eby has encouraged affected parties to
come forward.
Attorney General Niki Sharma said
she had heard of the case described
by Loo, and asked her staff to find out
more.
“That’s part of the work that we are
doing,” Sharma said. “We are looking
into all the potential impacts here.”
Sharma said later that government
hasn’t “ruled out anything” when asked
whether the government would give fi-
nancial support to property owners af-
fected by the ruling.
“We are very seized with this issue
and we are working through all the
ways that we can support people,” she
said.
On Wednesday, Eby said the province
would seek a stay on the August ruling,
which was already suspended for 18
months by the judge in the case, in or-
der to give the Cowichan, Canada and
Richmond time to make “necessary ar-
rangements.”
— The Canadian Press
NONO SHEN
AND WOLFGANG DEPNER
Project denied funding over title ruling
uncertainty, B.C. councillor says
DARRYL DYCK / THE CANADIAN PRESS FILES
Industrial lands
that fall within
the boundaries of
a Cowichan Nation
Aboriginal title claim
are seen in an aerial
view in Richmond,
B.C. last August.
;